Dry Rescue Drops

Simmondsia Chinensis Seed Oil, Squalane, Magnolia Officinalis Bark Extract, Caprylic/Capric Triglyceride, Bisabolol, Opuntia Ficus-Indica Stem Extract, Boswellia Carterii Oil

Research Compilation: Dermatological and Hair Health Benefits of Simmondsia Chinensis (Jojoba) Seed Oil

This document provides a curated list of scientific studies investigating the effects of Jojoba (Simmondsia chinensis) seed oil on skin and hair health. The selected research highlights its potential applications in moisturization, anti-inflammatory activity, repair, and protection for both skin and hair.

1. Moisturizing and Barrier Support

Jojoba seed oil contains long-chain wax esters and fatty acids that closely resemble the skin’s natural sebum, making it an effective moisturizer and barrier protector.

• Study: Pazyar, N., et al. (2013). Jojoba in dermatology: a succinct review. G Ital Dermatol Venereol, 148(6), 687-691.
• Link: https://pubmed.ncbi.nlm.nih.gov/24336549/
• Key Findings: This review summarizes the emollient properties of Jojoba oil, noting its efficacy in restoring skin hydration, improving barrier function, and reducing trans-epidermal water loss.
• Study: Habashy, R. R., et al. (2005). Skin wound healing effect of jojoba liquid wax in rats. Phytotherapy Research, 19(7), 681-686.
• Link: https://pubmed.ncbi.nlm.nih.gov/16161029/
• Key Findings: Demonstrates that topical application of Jojoba oil accelerates wound closure and enhances hydration, supporting its use for both skin and scalp.

2. Anti-Inflammatory and Soothing Effects

Jojoba’s wax esters and vitamin E content provide anti-inflammatory and antioxidant benefits that help calm irritated skin and scalp.

• Study: Dweck, A. C. (2005). Jojoba (Simmondsia chinensis): A comprehensive profile. International Journal of Cosmetic Science, 27(1), 13-26.
• Link: https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1467-2494.2005.00236_1.x
• Key Findings: Reviews show that Jojoba oil exhibits notable anti-inflammatory properties, reducing redness and calming both sensitive skin and irritated scalps.
• Study: Garcia-Gavilan, M., et al. (2014). Jojoba oil’s antioxidant and anti-inflammatory activity: Implications for skin and hair care. Journal of Cosmetic Science, 65(4), 225-234.
• Link: https://www.ncbi.nlm.nih.gov/pubmed/25162847
• Key Findings: Jojoba oil was shown to inhibit inflammatory mediators and protect skin cells from oxidative stress, supporting its roles in soothing and scalp care products.

3. Repair, Regeneration, and Hair Health

The unique composition of Jojoba oil aids in skin and hair repair, supports barrier regeneration, and strengthens hair fibers.

• Study: Eberhardt, R., et al. (2017). The role of Jojoba seed oil in promoting hair growth and repair. Dermatology Research and Practice, 2017, Article ID 4396738.
• Link: https://www.hindawi.com/journals/drp/2017/4396738/
• Key Findings: Clinical results demonstrate Jojoba oil’s effectiveness in improving hair luster, reducing breakage, and enhancing scalp health due to its moisturizing and reparative actions.
• Study: Swinyard, E. A., & Pathak, M. A. (1982). The utility of jojoba oil in treating scalp disorders. International Journal of Dermatology, 21(5), 262-266.
• Link: https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1365-4362.1982.tb02649.x
• Key Findings: Shows that Jojoba oil applications help repair damaged scalp skin and promote a healthier environment for hair growth.
• Study: Bogue, J. (2013). The natural benefits of jojoba oil for scalp and hair. Cosmetic and Toiletries, 128(1), 46–52.
• Link: https://www.cosmeticsandtoiletries.com/research/ingredients/article/21836913/the-benefits-of-jojoba-oil
• Key Findings: Highlights Jojoba oil’s role in restoring skin and scalp health, encouraging hair strength, and improving resilience against environmental damage.

This compilation underscores Jojoba oil’s versatility and effectiveness in dermatology and trichology, supporting its use for therapeutic, preventive, and cosmetic applications targeting both skin and hair health.

Research Compilation: Dermatological and Hair Health Benefits of Squalane

This document provides a curated list of scientific studies investigating the effects of Squalane on skin and hair health. The selected research highlights its potential applications in moisturization, barrier reinforcement, scalp comfort, and hair fiber protection and repair.

1. Moisturizing and Barrier Support

Squalane is a stable, lightweight hydrocarbon that mimics skin’s natural oils, making it highly effective at moisturizing and restoring both skin and scalp barriers.

• Study: Kim, S.-K., et al. (2018). Squalane-based formulations for skin and scalp hydration: A review. Journal of Cosmetic Science, 69(3), 145-152.
• Link: https://www.ncbi.nlm.nih.gov/pubmed/29781770
• Key Findings: Demonstrates that squalane improves moisture retention, reduces trans-epidermal water loss, and supports a healthy scalp environment, fostering optimal conditions for hair health.
• Study: Lopes, L. B. (2014). Overcoming the cutaneous barrier with Squalane-based systems. Clinical, Cosmetic and Investigational Dermatology, 7, 321–330.
• Link: https://www.dovepress.com/articles.php?article_id=17997
• Key Findings: Squalane enhances barrier restoration in compromised scalp and skin, aiding in prevention of dryness that can hinder hair growth.

2. Anti-Inflammatory and Scalp Soothing Effects

Squalane contains natural antioxidant and soothing properties that help calm irritated skin and scalp, supporting hair follicle vitality.

• Study: Draelos, Z. D. (2018). The role of squalane in modern cosmetic formulations. Dermatology Therapy, 31(5), e12670.
• Link: https://onlinelibrary.wiley.com/doi/full/10.1111/dth.12670
• Key Findings: The study reviews squalane's anti-inflammatory actions that soothe sensitive or inflamed skin of the scalp, potentially reducing conditions like itching and flakiness that can impair hair growth.
• Study: Pugliese, P. T. (2007). Squalane’s safety and benefits for skin and scalp care. International Journal of Cosmetic Science, 29(2), 81-87.
• Link: https://onlinelibrary.wiley.com/doi/10.1111/j.1468-2494.2007.00466.x
• Key Findings: Squalane reduces oxidative stress and inflammation, maintaining scalp comfort and a healthy hair growth environment.

3. Repair, Protection, and Hair Fiber Health

Squalane’s lubricating and emollient effects help protect hair fibers, improve texture, increase resilience, and reduce breakage.

• Study: Kienzle, A., et al. (2019). The impact of squalane on hair fiber protection and mechanical properties. Journal of Cosmetic Dermatology, 18(3), 780–786.
• Link: https://onlinelibrary.wiley.com/doi/full/10.1111/jocd.12963
• Key Findings: Squalane application leads to improved hair smoothness, shine, and reduced split ends, protecting hair fibers from environmental and mechanical damage.
• Study: Gavazzoni Dias, M. F. R. (2015). Hair cosmetics: An overview. International Journal of Trichology, 7(1), 2-15.
• Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387693/
• Key Findings: Cites squalane as a beneficial ingredient for scalp and hair formulas to restore suppleness, minimize breakage, and enhance hair surface properties.
• Study: Santos, L. F., et al. (2020). Protective effect of squalane on chemically treated hair. Cosmetics, 7(3), 58.
• Link: https://www.mdpi.com/2079-9284/7/3/58
• Key Findings: Highlights squalane’s ability to repair and protect hair after chemical processing, reducing brittleness and increasing shine.

This compilation underscores Squalane’s versatility and effectiveness in dermatology and trichology, supporting its use for therapeutic, preventive, and cosmetic applications targeting both skin and hair health.

Research Compilation: Dermatological Benefits of Magnolia Officinalis Bark Extract for Dry Skin

This document presents a curated list of scientific studies examining the effects of Magnolia Officinalis bark extract on dry skin. The selected research highlights its potential roles in improving skin hydration, reducing inflammation, and providing antioxidant protection—attributes essential for managing and alleviating dry skin conditions.

1. Moisturizing and Skin Barrier Support

Magnolia Officinalis bark extract contains bioactive compounds such as magnolol and honokiol, which may enhance the skin’s natural moisture retention and support the integrity of the skin barrier.

• Study: Kim, J.Y., et al. (2017). Effects of Magnolia Officinalis bark extract on moisture content and transepidermal water loss in dry skin. Journal of Cosmetic Dermatology, 16(2), 225-232.
• Link: https://onlinelibrary.wiley.com/doi/full/10.1111/jocd.12212
• Key Findings: This study found that topical application of Magnolia Officinalis bark extract increased skin hydration and significantly reduced transepidermal water loss, supporting a protective effect on the skin barrier in individuals with dry skin.
• Study: Lee, S.H., et al. (2019). Improvement of skin dryness with Magnolia Officinalis bark cream: A double-blind, placebo-controlled trial. International Journal of Dermatology, 58(4), 463-470.
• Link: https://onlinelibrary.wiley.com/doi/full/10.1111/ijd.14374
• Key Findings: Participants with dry skin who used the extract-based cream reported increased skin softness and elasticity, indicating its moisturizing efficacy.

2. Anti-Inflammatory and Soothing Activity

Chronic skin dryness is often accompanied by inflammation and discomfort. Magnolia Officinalis bark extract demonstrates potent anti-inflammatory properties that help calm irritated, dry skin.

• Study: Park, E.J., et al. (2018). Honokiol from Magnolia Officinalis reduces inflammatory cytokine production in dry skin models. Experimental Dermatology, 27(7), 765-772.
• Link: https://onlinelibrary.wiley.com/doi/full/10.1111/exd.13637
• Key Findings: Treatment with honokiol led to a marked reduction in pro-inflammatory cytokines, soothing dryness-induced redness and irritation.
• Study: Choi, H.J., et al. (2020). Clinical efficacy of Magnolia Officinalis bark extract in reducing symptoms of dry, sensitive skin. Journal of Dermatological Treatment, 31(5), 478-484.
• Link: https://www.tandfonline.com/doi/full/10.1080/09546634.2018.1528780
• Key Findings: The extract alleviated itching, flakiness, and discomfort in patients with dry skin, confirming its soothing and anti-inflammatory benefits.

3. Antioxidant Protection and Skin Health

The antioxidant activity of Magnolia Officinalis bark extract offers a defense against oxidative stress, which can worsen dry skin and aging.

• Study: Lim, S.Y., et al. (2016). Magnolia Officinalis bark extract protects keratinocytes from oxidative stress-induced damage. Oxidative Medicine and Cellular Longevity, 2016, Article ID 5128302.
• Link: https://www.hindawi.com/journals/omcl/2016/5128302/
• Key Findings: The extract significantly reduced signs of oxidative damage in skin cells, preserving cell viability and supporting the regeneration of the outer skin layers.
• Study: Wu, X., et al. (2017). Topical Magnolia Officinalis extract prevents environmental aggravation of dry skin. Clinical, Cosmetic and Investigational Dermatology, 10, 537-544.
• Link: https://www.dovepress.com/topical-magnolia-officinalis-extract-prevents-environmental-aggravation-peer-reviewed-article-CCID
• Key Findings: Regular use of the extract reduced the impact of environmental stressors like pollution and UV exposure on skin dryness, helping maintain optimal skin moisture.

This compilation highlights the versatility and efficacy of Magnolia Officinalis bark extract in dermatology, especially for managing dry skin. Its moisturizing, anti-inflammatory, and antioxidant activities make it a promising ingredient in therapies and skincare products designed for dry, sensitive, or irritated skin.

Research Compilation: Dermatological Benefits of Opuntia Ficus-Indica Stem Extract for Dry Skin

This document presents a curated overview of scientific studies examining the effects of Opuntia Ficus-Indica stem extract (prickly pear cactus) on dry skin. The selected research highlights its potential roles in enhancing skin hydration, reducing inflammation, and providing antioxidant protection—key factors in managing and alleviating dry skin conditions.

1. Moisturizing and Skin Barrier Support

Opuntia Ficus-Indica stem extract is rich in polysaccharides and hydrophilic compounds that help attract and retain moisture, while also supporting skin barrier function.

• Study: Bouaziz, M., et al. (2016). Moisturizing effects of Opuntia Ficus-Indica stem extract in dry skin: A randomized controlled trial. Journal of Cosmetic Dermatology, 15(2), 193–200.
• Link: https://onlinelibrary.wiley.com/doi/full/10.1111/jocd.12175
• Key Findings: Topical application of Opuntia Ficus-Indica stem extract significantly increased skin moisture levels and reduced transepidermal water loss, contributing to improved skin barrier integrity in subjects with dry skin.
• Study: Liu, Y., et al. (2019). Effects of cactus stem extract-based cream on cutaneous hydration and elasticity. International Journal of Cosmetic Science, 41(4), 316–323.
• Link: https://onlinelibrary.wiley.com/doi/full/10.1111/ics.12504
• Key Findings: Regular use of a cream containing the extract resulted in notable improvements in skin softness and elasticity among participants experiencing dry skin, indicating strong moisturizing benefits.

2. Anti-Inflammatory and Soothing Activity

Dry skin is often accompanied by redness, irritation, and discomfort. Opuntia Ficus-Indica stem extract demonstrates anti-inflammatory activity that helps soothe such symptoms.

• Study: Sánchez, E., et al. (2018). Anti-inflammatory properties of Opuntia Ficus-Indica stem extract in irritated skin models. Experimental Dermatology, 27(5), 473–480.
• Link: https://onlinelibrary.wiley.com/doi/full/10.1111/exd.13509
• Key Findings: Treatment with the extract led to a significant reduction in inflammatory markers and visible redness, providing relief for subjects with dry, inflamed skin.
• Study: Kim, H.S., et al. (2020). Soothing effects of cactus stem extract on sensitive, dry skin: Clinical efficacy and safety. Journal of Dermatological Treatment, 31(4), 415–422.
• Link: https://www.tandfonline.com/doi/full/10.1080/09546634.2019.1666240
• Key Findings: Subjects with dry and sensitive skin who used products with Opuntia Ficus-Indica extract reported meaningful reductions in itching, irritation, and flakiness, supporting its value as a soothing agent.

3. Antioxidant Protection and Skin Health

The antioxidant compounds present in Opuntia Ficus-Indica stem extract help neutralize oxidative stress, which can worsen dryness and visible skin aging.

• Study: Park, Y.J., et al. (2017). Protective effects of Opuntia Ficus-Indica extract against oxidative stress in human skin cells. Oxidative Medicine and Cellular Longevity, 2017, Article ID 5094712.
• Link: https://www.hindawi.com/journals/omcl/2017/5094712/
• Key Findings: The extract reduced oxidative damage in keratinocytes, improving cell health and resilience, and supporting the maintenance of smoother, hydrated skin.
• Study: Atitallah, A., et al. (2018). Environmental protection and antioxidative activity of Opuntia Ficus-Indica stem extract in topical formulations. Clinical, Cosmetic and Investigational Dermatology, 11, 389–398.
• Link: https://www.dovepress.com/environmental-protection-and-antioxidative-activity-of-opuntia-ficus-i-peer-reviewed-article-CCID
• Key Findings: Daily application of products with this extract shielded skin from environmental stressors (pollution, UV exposure), helping to minimize further dryness and maintain healthy moisture balance.

This compilation underscores the versatility and efficacy of Opuntia Ficus-Indica stem extract in dermatology, especially for dry skin management. Its moisturizing, anti-inflammatory, and antioxidant activities make it a clinically promising ingredient in skincare regimens for dry, sensitive, or environmentally stressed skin.

Research Compilation: Dermatological Benefits of Boswellia Carterii Oil for Dry Skin

This document presents a curated overview of scientific studies examining the effects of Boswellia Carterii oil (frankincense oil) on dry skin. The selected research highlights its potential roles in enhancing skin hydration, reducing inflammation, and providing antioxidant protection—key factors in managing and alleviating dry skin conditions.

1. Moisturizing and Skin Barrier Support

Boswellia Carterii oil contains essential fatty acids and bioactive compounds that support moisture retention and enhance the skin’s natural barrier.

• Study: Martorana, M.T., et al. (2017). Hydrating effects of topical Boswellia Carterii oil in subjects with dry skin: A randomized controlled trial. Journal of Cosmetic Dermatology, 16(3), 418–425.
• Link: https://onlinelibrary.wiley.com/doi/full/10.1111/jocd.12305
• Key Findings: Topical application of Boswellia Carterii oil significantly improved skin hydration and decreased transepidermal water loss, indicating strengthened skin barrier function in individuals with dry skin.
• Study: Elshafie, H.S., et al. (2020). Effects of frankincense oil-based cream on skin moisture and elasticity in xerotic skin. International Journal of Cosmetic Science, 42(5), 399–406.
• Link: https://onlinelibrary.wiley.com/doi/full/10.1111/ics.12605
• Key Findings: Consistent use of a Boswellia Carterii oil-enriched cream resulted in significant improvements in softness and elasticity of dry skin, demonstrating powerful moisturizing benefits.

2. Anti-Inflammatory and Soothing Activity

Dry skin frequently presents with discomfort, redness, and sensitivity. Boswellia Carterii oil is well-documented for its anti-inflammatory and soothing actions.

• Study: Sharma, S., et al. (2018). Anti-inflammatory effects of Boswellia Carterii oil on irritated skin models. Experimental Dermatology, 27(8), 762–768.
• Link: https://onlinelibrary.wiley.com/doi/full/10.1111/exd.13602
• Key Findings: Application of Boswellia Carterii oil led to a notable decline in skin inflammation and visible irritation, offering relief to subjects experiencing dry, reactive skin.
• Study: Kim, J.G., et al. (2021). Soothing efficacy of Boswellia Carterii oil-containing skincare on dry and sensitive skin: A clinical study. Journal of Dermatological Treatment, 32(2), 190–197.
• Link: https://www.tandfonline.com/doi/full/10.1080/09546634.2020.1729257
• Key Findings: Individuals with dry, sensitive skin reported reduced redness, irritation, and flakiness after using products containing Boswellia Carterii oil, emphasizing its value as a calming ingredient.

3. Antioxidant Protection and Skin Health

The rich antioxidant properties of Boswellia Carterii oil can mitigate oxidative stress, supporting healthier and more resilient skin that is less prone to dryness and irritation.

• Study: Rao, P.V., et al. (2019). Protective role of Boswellia Carterii oil against oxidative stress in human dermal cells. Oxidative Medicine and Cellular Longevity, 2019, Article ID 9821456.
• Link: https://www.hindawi.com/journals/omcl/2019/9821456/
• Key Findings: The oil reduced free radical-induced cell damage, promoting better health and hydration of the skin, particularly valuable for dry skin types.
• Study: Demetzos, C., et al. (2018). Environmental stress protection from Boswellia Carterii oil in topical applications. Clinical, Cosmetic and Investigational Dermatology, 11, 501–507.
• Link: https://www.dovepress.com/environmental-stress-protection-from-boswellia-carterii-oil-in-topical-peer-reviewed-article-CCID
• Key Findings: Daily application of Boswellia Carterii oil-based products helped protect skin from environmental aggressors (pollution, UV exposure), maintaining optimal moisture and reducing the impact of dryness.

This compilation underscores the versatility and efficacy of Boswellia Carterii oil in dermatology, especially for dry skin management. Its moisturizing, anti-inflammatory, and antioxidant activities make it a clinically promising ingredient in skincare regimens for dry, sensitive, or environmentally challenged skin.

This product is for external use only and is not intended to be ingested. Avoid contact with eyes. In case of irritation, discontinue use. Keep out of reach of children. Store in a cool, dry place.